Bioprocess

XY-TEK non-invasive ultrasonic sensors enable rapid and precise liquid flow measurement in both upstream and downstream bioprocessing. We provide a range of calibration and customization options to ensure optimal performance tailored to specific biopharmaceutical needs, such as TFF, HPLC, protein purification, and liquid feeding machines.

CG Series Clamp-on Ultrasonic Flow Sensors/Flow Meters for Biopharmaceutical

In biopharmaceutical production, efficiently managing bio-liquids, such as nutrient media, into and out bioreactors is essential for maintaining optimal system performance.

The CG series clamp-on ultrasonic flow sensors/flow meters provide the biopharmaceutical industry with a non-invasive solution for verifying the performance of fluid pumps in the bioprocessing systems, monitoring pipeline integrity, and facilitating automated, intelligent bio-production management.

CG series clamp-on ultrasonic flow sensors/flow meters do not directly contact the fluid being measured, allowing for repeated use without costly disinfection or gamma irradiation.

The non-invasive design makes them especially suitable for high-sanitization environments, such as single-use biopharmaceutical systems.

Featuring a compact design, the CG series clamp-on ultrasonic flow sensors/flow meters can be easily clamped onto flexible plastic tubing. They enable accurate and reliable measurement of bio-liquid without interrupting the existing setup.

Industry Challenges

  • Contamination

    Maintaining hygiene and sterility is critical in biopharmaceutical production. Any contaminants introduced during measurement can compromise product quality.  The bio-media flow rate measurement meter need to be non-invasive and easy to clean or sterilize to avoid direct contact with the measured liquids.

    01
  • Flow Rates

    Flow rates can vary significantly due to changes in production cycles, batch sizes, or formulation adjustments. Accurately measuring these variable flow rates requires measurement technologies that can adapt and provide reliable data regardless of fluctuations, ensuring consistent product quality.

    02
  • Air Bubbles

    Air bubbles and particulate matter in the bio-fluid can interrupt flow and affect measurement accuracy. This is particularly relevant in biopharmaceutical processes where precise dosing and mixing are critical.

    03

Application Overview

XY-TEK CG series ultrasonic flow sensors/flow meters can be used in the following bioprocess:

Application Highlights

  • Hygienic and Sterile Design

    The CG series clamp-on ultrasonic flow sensors/flow meters feature a non-invasive design that ensures no direct contact with the measured liquid, maintaining the highest standards of hygiene and sterility.

  • Compact and Efficient

    With a compact size that integrated circuits and advanced computing systems, CG series clamp-on design are easy for installation, making them ideal for liquid flow rate measurement in biopharmaceutical equipment.

  • Minimal Pressure Loss

    The clamp-on design eliminates clogging, steering, and dead space, resulting in minimal fluid pressure loss.

  • Versatile Output Options

    The CG series clamp-on ultrasonic flow sensor / flow meters offers multiple output methods, including analog, frequency, switching and RS485, allowing for seamless integration with existing customer systems. Switching output can be easily configured for flow switch, bubble detection, dosing, and flow rate output.

  • Effortless Installation

    Designed for convenience, the CG series clamp-on ultrasonic flow sensors/flow meters can be easily clamped onto the outside of the tubing without disconnecting any lines. This approach eliminates system downtime and significantly enhances installation and dismantling efficiency.

  • High Accuracy

    Flow range: 10mL/min~100L/min. Measurement accuracy up to ± 1%.Supporting bi-directional measurements.


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