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Bioreactors

Bioreactors serve as controlled environments where biological reactions take place, playing a pivotal role in the production of pharmaceuticals, vaccines, and various bioproducts.

These sophisticated systems utilize microorganisms, cells, or enzymes to produce desired outcomes under optimal growth conditions such as temperature, pH, and nutrient supply. In the biopharmaceutical industry, bioreactors are essential for the controlled scaling of biological processes, ensuring consistent quality and safety in final products.

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Industry Challenges

Contamination Risk

Invasive bio-media measurements can introduce contaminants, affecting the quality of the final bio-products.

01
Operational Downtime

Traditional sensors often require probe insertions that disrupt processes and necessitate maintenance, leading to costly downtime.

02
Inconsistent Measurements

Maintaining precise control over fluid dynamics is critical; discrepancies can compromise research outcomes and product integrity.

03
Flow Pressure

Excessive flow pressure can cause shear stress on microbial， which may decrease the yield of the desired bioproduct.

04

Application Overview

In response to these challenges, the industry is increasingly turning to advanced solutions for flow measurement. Among these, the CG Series Non-Invasive Ultrasonic Flow Sensors stand out as a game-changing technology. These sensors not only provide accurate flow measurement but also navigate around common issues associated with traditional methods, ensuring the integrity and safety of bioprocessing operations.

Application Highlights

No Contamination

The non-invasive nature of the CG series minimizes the risk of contamination during aseptic filling, enhancing product safety and quality.The non-invasive measurement reduces the risk of contaminating sensitive biological media. Unlike inline measurement sensors, which can introduce foreign substances or induce cell damage, CG series sensors maintain the purity of the bio-media, which is essential for generating reliable experimental data and high-quality bio-products.
Reduced Downtime

The CG Series allows continuous flow measurement without complex installations or disruptive maintenance procedures.
Consistent Results

This consistency is crucial for ensuring that data is reliable for decision-making, conducting analyses, and validating processes, ultimately contributing to improved outcomes in biopharmaceutical production.
Cost EfficiencyWide Measurement Range

CG Series sensors are designed to accommodate a broad flow rate range making them suitable for applications ranging from low flow rates in cell cultures to high flow rates in large-scale fermentation processes.
Cost EfficiencyWide Measurement RangeHigh Accuracy±3%

CG Series ultrasonic flow sensors effectively capture transient flow characteristics essential for dynamic biological processes. This capability ensures that any rapid changes in flow conditions are accurately monitored, facilitating better process control.

Advantages

Minimal Pressure Loss

The design of the CG Series prevents significant pressure loss in the system, which is crucial for maintaining optimal conditions within bioreactors, which can directly impact cell metabolism and product yields.
Versatility Across Bioreactor Configurations

CG series sensors are adaptable to various bioreactor setups, including stirred tanks, bioreactors, and membrane bioreactors, allowing for tailored solutions that meet diverse bioprocessing requirements.
Low Maintenance

CG Series sensors typically demand less maintenance than traditional contact-based sensors, leading to lower labor costs and increased efficiency in bioprocessing environments.
Multi-Functional Capabilities

Support bubble detection and alerts, bi-directional flow measurement, and optional output modes to integrate seamlessly with existing systems, offering enhanced functionality.