Liquid Chromatography/HPLC is an instrument used to separate, detect, and analyze compounds. It does this by splitting a mixture into parts. Then, it does a quantitative and qualitative analysis of each part.

Scientists and researchers use chromatographs in fields like chemistry, bio-downstream process development, and pharmacy. They use liquid chromatography to learn about the composition, structure, and properties of samples.

In single-use pharmaceutical processes, liquid chromatographs play a crucial role in drug component analysis, quality control, research and development, metabolic studies, etc., making drug research and production more precise, efficient, and reliable.

Accurate flow rate measurement is crucial, it shows how well liquid chromatographs perform.

Traditional measurement methods present multi challenges to the accuracy of the results.

1.Flow rate fluctuations

Fluid flow rates in chromatographic instruments may fluctuate. This leads to instability and inaccuracy in flow rate measurements.

2.Changes in liquid properties

During chromatography, the fluid's properties can change. This happens due to shifts in temperature, pressure, or composition. These changes affect the accuracy of flow rate measurements.

3.Liquid viscosity

Some fluids being measured may have high viscosity, which can affect the fluid's flow performance in the chromatograph, leading to difficulties in flow rate measurements.

4.Foam and bubbles

Bubbles or foam may be present in the chromatograph, which can interfere with flow rate measurements and lead to inaccurate results.

5.Liquid contamination

Maintaining the purity and sterility of the liquid is crucial in chromatographic analysis. During flow rate measurements, it is essential to ensure that all connecting components and tubings are sterile to prevent any bacteria or contaminants from entering the sample.

XY-TEK CG Ultrasonic Flow Sensor / Flow Meter  & TGU series Ultrasonic Flow Sensor / Flow Meter  can address these challenges and add advantages to liquid chromatography/HPLC.

1.Clamp-on design, easy to use

The CG series clamp on ultrasonic flow sensor / flow meter can be organically combined with pumps, tubings, and related sensors required by the chromatograph on a single frame, with optional fixed or mobile installation.

2.Non-invasive flow rate measurement, meeting high hygiene requirements

The CG series clamp on ultrasonic flow sensor / flow meter does not contact the measured fluid, reducing the risk of cross-infection or contamination to a minimum and meeting the requirements for liquid purity and sterility in biopharmaceutical processes.

3.Flexible configuration

The CG series clamp on ultrasonic flow sensor / flow meter provides 12 different tubing diameter options. The flow sensors support customization and OEM based on customer specific needs, whether they are used independently or connected upstream and downstream devices.

4.Wide flow rate range

The CG series clamp on ultrasonic flow sensor / flow meter can measure flow rates from 25 mL/min to 1000L/min.

5.High Flow Rate Measurement Accuracy

The CG series clamp on ultrasonic flow sensor / flow meter has the high flow rate measurement accuracy as ±3%.

6.Multiple Output

The CG series clamp on ultrasonic flow sensor / flow meter can be seamlessly integrated with customer chromatographic analysis systems.

7.R&D and Manufactured by XY-TEK

XYTEK can provide faster lead times for the ultrasonic flow sensor / flow meters, and in-time good technical support and after-sales service.

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