CG series Non-Invasive Ultrasonic Flow Sensors for Bioreactors

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Introduction to Bioreactors

Bioreactors are controlled environments where biological reactions occur, often used in the production of pharmaceuticals, vaccines, and other bioproducts.

These systems utilize microorganisms, cells, or enzymes to produce a desired product under optimal growth conditions, including temperature, pH, and nutrient supply. Bioreactors play a critical role in the biopharmaceutical industries for the controlled scaling of biological processes, which is essential for consistent quality and safety in the final products.

Measured Media in Bioreactors

In bioreactors, the media being measured typically includes nutrient-rich solutions, cell culture fluids, and fermentation broths. These bio-media contain various components, such as glucose, salts, amino acids, and other nutrients necessary for the growth of microbial or mammalian cells.

Accurate flow measurement and control of the bio-liquids are vital for maintaining optimal conditions within the bioreactor and ensuring the efficiency of the biological processes.

The Importance of Non-Invasive Flow Measurement in Bioreactor

Non-invasive ultrasonic flow sensors have become increasingly important in measuring the fluid flow within bioreactors. Some key reasons include:

1.0 Contamination

Non-invasive measurement minimizes the risk of contamination or alteration of the biological media. Inline measurement sensors can introduce foreign substances or cause cell damage, affecting the validity of experimental data and the quality of the bio-product.

2. Reduced Downtime

Traditional invasive measurement sensors often require the insertion of probes or other instruments into the flow path, which may disrupt operations or require system shutdowns for maintenance. CG series non-invasive sensors eliminate this step, allowing continuous flow measurement without interruptions.

3. Repeatable Result

Precise control of the bio-media in and out is critical in bioreactors. CG series ultrasonic flow sensors provide highly consistent measurements over time, which is vital for ensuring that data collected from the sensor can be trusted for making decisions, conducting analyses, and validating processes.

4. Wide measurement Range

CG series non-invasive ultrasonic flow sensor support measures flow rate range from 1ml to 100,000ml/min, suitable for very low flow rates in cell cultures to higher rates in large-scale fermentation processes.

5. High Accuracy 3%

CG series ultrasonic flow sensors can capture transient flow characteristics that are crucial in dynamic biological processes where flow conditions may change rapidly.

Advantages of CG series Non-Invasive ultrasonic flow sensor Over another sensor

CG series non-invasive ultrasonic flow sensors offer several advantages compared to conventional flow measurement techniques used in bioreactors:

1.Minimal Pressure Loss

Non-invasive measurements do not introduce significant pressure losses into the system. This is particularly important in bioreactors, where maintaining optimal pressure conditions can affect cell metabolism and product yields.

2.Multi-scenarios

CG series ultrasonic flow sensors can be implemented in various bioreactor configurations, including stirred tanks, bubble column bioreactors, and membrane bioreactors, making them adaptable to different bioprocessing requirements.

3.Low Maintenance Requirements

CG series ultrasonic flow sensors typically require less maintenance than contact-based sensors, reducing labor costs and improving efficiency in bioprocessing environments.

4.Multi-function

Support bubble detection and alert, support bi-directional flow measurement, and optional output mode to compact with the 3rd system.

By providing accurate, reliable, and contamination-free measurements, CG series ultrasonic flow sensors enhance the efficiency and safety of bioreaction processes.

Contributes to better process control and also ensures the integrity and quality of biopharmaceutical products.